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First Steps After Diagnosis of Cancer
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| Welcome
to The Cancer Information Network |
Adult
Brain Tumor Treatment Information
for Physicians
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Important: This
information is intended mainly for use by doctors and other health care
professionals. If you have questions about this topic, you can ask your
doctor, or call the Cancer Information Service at 1-800-4-CANCER
(1-800-422-6237).
ADULT MENINGIOMA
Meningioma is usually curable when resectable.
Treatment options:
Standard:
- 1. Surgery.[1]
2. Surgery plus radiation therapy (in selected cases, such as for
patients with known or suspected residual disease or with recurrence
after previous surgery).[2-4]
References:
- Black PM: Meningiomas. Neurosurgery 32(4): 643-657,
1993.
Wara WM, Sheline GE, Newman H, et al.: Radiation
therapy of meningiomas. American Journal of Roentgenology, Radium
Therapy and Nuclear Medicine 123(3): 453-458, 1975.
Barbaro NM, Gutin PH, Wilson CB, et al.:
Radiation therapy in the treatment of partially resected meningiomas.
Neurosurgery 20(4): 525-528, 1987.
Taylor BW, Marcus RB, Friedman WA, et al.: The
meningioma controversy: postoperative radiation therapy. International
Journal of Radiation Oncology, Biology, Physics 15(2): 299-304, 1988.
Malignant meningioma, hemangiopericytoma, and papillary
meningioma
The prognosis for patients with malignant meningioma is worse than for
the more well-differentiated meningiomas because complete resections are
less common and the proliferative capacity is greater.[1]
Treatment options:
Standard:
- Surgery plus radiation therapy.
Under clinical evaluation:
- Patients with brain tumors that are either infrequently curable or
unresectable should be considered candidates for clinical trials that
evaluate interstitial brachytherapy, radiosensitizers, hyperthermia, or
intraoperative radiation therapy in conjunction with external-beam
radiation therapy to improve local control of the tumor and/or for
studies that evaluate new drugs and biological response modifiers
following radiation therapy.
References:
- Alvarez F, Roda JM, Perez-Romero M, et al.: Malignant
and atypical meningiomas: a reappraisal of clinical, histological, and
computed tomographic features. Neurosurgery 20(5): 688-694, 1987.
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